Anifrolumab (Saphnelo)

Saphnelo (Anifrolumab) is a biologic medicine that is used to treat lupus. It works by suppressing part of the body’s immune system.

Saphnelo works by blocking type 1 interferon, which is a type of signalling protein (called a cytokine), that is a driver of the disease activity in lupus.

Taking Saphnelo

Saphnelo is given as an intravenous infusion (IV) by a trained nurse in a clinic.

The manufacturer of Saphnelo offers a support program to Canadian patients that are prescribed the medication:

Patient support program enrolment forms

Important Tests and Risks




Saphnelo Quick Reference Guide


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