Cyclophosphamide (Cytoxan)

Cyclophosphamide is a medication that works by suppressing the immune system. It is an important treatment option for serious autoimmune diseases.

Cyclophosphamide may be used to treat several different types of rheumatic disease including Systemic Lupus Erythematosus (SLE), diseases that inflame the walls of blood vessels (forms of vasculitis), and sometimes for Rheumatoid Arthritis.

Cyclophosphamide is best known for its other use as a chemotherapy drug that is used to treat certain types of cancers.

Taking Cyclophosphamide

Cyclophosphamide is available in two forms: 50mg tablets, and intravenous infusion.

Important Tests and Risks




Watch Dr. Andy Thompson, a Canadian rheumatologist, introduce Cyclophosphamide in this short video:


Cyclophosphamide Quick Reference Guide