Ustekinumab (Wezlana)

Wezlana (Ustekinumab) is a biologic medicine that suppresses the immune system in order to treat psoriatic arthritis and psoriasis.

Wezlana works by blocking two signalling proteins called cytokines named interleukin-12 (IL-12) and interleukin-23 (IL-23). These cytokines regulate the body’s immune system and are related to its inflammatory response.

Taking Wezlana

Wezlana comes in a pre-filled syringe for subcutaneous (under the skin) injection that can be administered at home.

Although some patients who take Wezlana can feel better quite quickly, in others it can take a little longer. It is important to keep taking this medicine as prescribed by a doctor.


Wezlana is a type of medicine that is called a biosimilar. A biosimilar is a type of biologic medication that is designed to be identical to an existing biologic medication, but is created using a different process.

Wezana is a biosimilar of Stelara. Both medications are known by the same generic name: ustekinumab. Biosimilars are often cheaper than the original medication.

Important Tests and Risks




Wezlana Quick Reference Guide


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