Rituximab (Ruxience)

Ruxience (rituximab) is a biologic medicine that treats the pain and swelling of arthritis by suppressing part of the body’s immune system.

Ruxience destroys a type of white blood cell that has a role in the body’s immune system called the B-cell.

Ruxience can help in the treatment of a wide variety of diseases including rheumatoid arthritis and other autoimmune diseases, some types of cancer, and ultimately any disease that involves unwanted activity from B-cells. Ruxience is also used to help prevent tissue rejection in organ transplant patients.


Ruxience is a type of medicine that is called a biosimilar. A biosimilar is a type of biologic medication that is designed to be identical to an existing biologic medication, but is created using a different process.

Ruxience is a biosimilar of Rituxan. Both medications are known by the same generic name: rituximab. Biosimilars are usually available at a lower price than the original medication.

Taking Ruxience

Ruxience is available as an intravenous (IV) infusion.

Some patients feel better soon after receiving the medication, but in others, it can take longer: up to 3 or 4 months.

Important Tests and Risks




Watch Canadian rheumatologist Dr. Andy Thompson introduce Ruxience.


Ruxience Quick Reference Guide


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