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Medications > Golimumab IV | Simponi IV > Golimumab IV | Simponi IV | Pictopamphlet

Golimumab IV | Simponi IV [Go-LIM-you-mab]

How to use this medication

What is it?

Some people with arthritis have too much TNF.  TNF is a protein found in the body that can cause pain and swelling in the joints. Golimumab IV is a biologic medicine that blocks TNF and helps the pain and swelling of arthritis.

Given by Intravenous (IV) Infusion

Golimumab IV is given by an intravenous infusion (IV) by a trained nurse.  Each infusion takes about 30 minutes.

Givne once every 8 weeks

You will receive an initial infusion and then a second infusion 4 weeks later.  Following this you will receive infusions every 8 weeks.

Give it some time

Although some patients can feel better quite quickly in others it can take a little longer. Keep taking your medication.

What you need to do

Stop if you have an infection

Golimumab IV can make it harder for you to fight off infections.  Call your doctor if:

  • You develop a fever
  • You think you have an infection
  • You are given antibiotics to treat an infection

Make sure to get tuberculosis testing

All patients should have a tuberculosis skin test & chest

x-ray before starting golimumab IV.  Talk to your doctor.

Get occasional blood tests

It is important to occasionally have your blood tested while taking golimumab IV. This is important to keep track of your arthritis and to make sure golimumab IV isn’t affecting your liver or blood counts.

Side effects & important things to know

Infusion reaction

Golimumab IV can rarely cause an allergic reaction during the infusion.


Golimumab IV should be stopped before surgery.  It can be restarted once things have healed and there is no sign of infection.  If you are having surgery, talk to your doctor about when to stop the medicine.

Pregnancy & Breastfeeding

Golimumab IV has not been studied in pregnancy.  Let your doctor know if you are planning to get pregnant or if you are breastfeeding.

Heart Problems

Golimumab IV may make a condition called congestive heart failure worse.  Tell your doctor if you have congestive heart failure.

Other very rare side effects

Patients have very rarely developed conditions of the nervous system (multiple sclerosis) and the immune system (lupus) while taking medications like golimumab IV.


Golimumab IV has very rarely been associated with the development of cancer.  Tell your doctor if you have had cancer in the past.

When should I call my doctor

Please call if you need to stop


  • If you feel sick and want to stop
  • If you are concerned about any side effects
  • If you want to or have already stopped the medicine

Other Reasons to Call your Doctor:

Fever or think you have an infection

If you are having surgery

If you become pregnant

If you plan to get any vaccinations

If you develop a rash