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Medications > Febuxostat | Uloric > Febuxostat (Uloric) – pictopamphlet

FEBUXOSTAT (Uloric) [Feb-UX-oh-stat]

How to use this medication

What is it

Febuxostat is a medication used to prevent attacks of gout. While taking this medicine it is important to have your blood tested occasionally.

Take it every day

This medicine is taken once a day.


It comes in 40 & 80 mg tablets.  The usual dose is one tablet (40 or 80 mg) taken once a day. Discuss your dose with your doctor.  In Canada only the 80 mg dose is available.

Be patient

It will take some time for the medicine to work. You may have flares of gout when starting. It is important to keep taking the medicine.

What you need to do

Get your blood tested

Have your blood tested EVERY MONTH OR TWO AFTER YOU START THE MEDICINE. This is important to make sure febuxostat isn’t irritating your liver.

Watch how much alcohol you drink.

Drinking alcohol can flare your gout. It is best to avoid alcohol completely.

Side effects & important things to know

Gout flare

When first started, febuxostat can increase gout flares. It is important to keep taking febuxostat. Your doctor can treat your flare of gout with different medicine.

Joint pain

Febuxostat can cause aching in the joints. This is rare.


Febuxostat agrees with most people. Rarely it can cause an upset stomach.

Skin rash

Febuxostat can rarely cause a rash.  Stop the medicine and let your doctor know if you develop a rash.  This is rare.

Heart & stroke

All patients with gout and those taking febuxostat should be aware of the risk of heart attack and stroke.  Discuss this with your doctor.

Pregnancy & breastfeeding

Febuxostat has not been studied in pregnancy.  Let your doctor know if you are planning to get pregnant or if you are breastfeeding.

Drug interactions

You must not take azathioprine, mercaptopurine, or theophylline while taking febuxostat. Always check with your doctor or pharmacist before starting any new medication.

When should I call my doctor

Please call if you need to stop

  • If you feel sick and want to stop
  • If you are concerned about any side effects
  • If you want to or have already stopped the medicine

Other Reasons to Call your Doctor:


Flare of gout

Pregnant or planning pregnancy

Other important information

Stopping Febuxostat

You can simply stop taking febuxostat. You do not need to wean off it. Please call your doctor if you stop the medication.