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Medications > Adalimumab | Humira > Adalimumab | Humira | Information

ADALIMUMAB (Humira) [Add-a-LIM-you-mab]

How to use this medication

What is it

Some people with arthritis have too much TNF.  TNF is a protein found in the body that can cause pain and swelling in the joints. Adalimumab is a biologic medicine that blocks TNF and helps the pain and swelling of arthritis.

Given by injection

Adalimumab is given by injection once every 2 weeks.  The normal dose is 40 mg every 2 weeks.

Take it once every two (2) weeks

Adalimumab is taken only once every two (2) weeks.  In some cases it may be given once a week.  You, a friend, or a family member can be taught how to give the injections.

Give it some time

Although some patients can feel better quite quickly in others it can take a little longer. Keep taking your medication.

What You Need to do

Stop if you have an infection

Adalimumab can make it harder for you to fight off infections.  Stop taking adalimumab and call your doctor if:

  • You develop a fever
  • You think you have an infection
  • You are given antibiotics to treat an infection.

Make sure to get tuberculosis testing

All patients should have a tuberculosis skin test & chest x-ray before starting adalimumab.  Talk to your doctor.

Get occasional blood tests

It is important to occasionally have your blood tested while taking adalimumab.  This is important to keep track of your arthritis and to make sure your blood counts are ok.

Side Effects & Important Things to Know

Injection site reaction

Adalimumab can rarely cause a reaction (redness, pain, & itching) at the injection site.  Tell your doctor if these are severe.


Adalimumab should be stopped before surgery.  It can be restarted once things have healed and there is no sign of infection.  If you are having surgery, talk to your doctor about when to stop the medicine.

Pregnancy & Breastfeeding

Adalimumab has not been studied in pregnancy.  Let your doctor know if you are planning to get pregnant or if you are breastfeeding.

Heart problems

Adalimumab may make a condition called congestive heart failure worse.  Tell your doctor if you have congestive heart failure.

Other very rare side effects

Patients have very rarely developed conditions of the nervous system (multiple sclerosis) and the immune system (lupus) while taking medications like adalimumab.


Adalimumab has very rarely been associated with developing cancer.  Tell your doctor if you have had cancer in the past.

When Should I call my Doctor

Please call if you need to stop

  • If you feel sick and want to stop
  • If you are concerned about any side effects
  • If you want to or have already stopped the medicine

Other Reasons to Call your Doctor:

Fever or think you have an infection

If you are having surgery

If you become pregnant

If you plan to get any vaccinations

If you develop a rash

Other Important Information

Stopping Adalimumab

You can simply stop taking adalimumab. You do not need to wean off it.